39.    Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW. (2015) Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nat Commun 6, 8013. 

38.    Hughes TS, Wilson HD, de Vera IMS, Kojetin DJ. (2015) Deconvolution of complex 1D NMR spectra using objective model selection. PloS One 10, e0134474.

37.    Wang Y, Kojetin D, and Burris TP. (2015) Anti-proliferative actions of a synthetic REV-ERBalpha/beta agonist in breast cancer cells. Biochem Pharmacol 96, 315-22.

36.    Marciano DP, Kuruvilla DS, Boregowda SV, Asteian A, Hughes TS, Garcia-Ordonez R, Corzo CA, Khan TM, Novick SJ, Park H, Kojetin DJ, Phinney DG, Bruning JB, Kamenecka TM, and Griffin PR. (2015) Pharmacological repression of PPARgamma promotes osteogenesis. Nat Commun 6, 7443

35.    Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, and Nettles KW. (2014) Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. eLife 3, e02057 

34.    Matta-Camacho E, Banerjee S, Hughes TS, Solt LA, Wang Y, Burris TP, and Kojetin DJ. (2014) Structure of REV-ERBbeta ligand-binding domain bound to a porphyrin antagonist. J Biol Chem 289, 20054-20066

33.    Kojetin DJ, and Burris TP. (2014) REV-ERB and ROR nuclear receptors as drug targets. Nat Rev Drug Discov 13, 197-216

32.    Hudson WH, Pickard MR, de Vera IM, Kuiper EG, Mourtada-Maarabouni M, Conn GL, Kojetin DJ, Williams GT, and Ortlund EA. (2014) Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate. Nat Commun 5, 5395

31.    Hughes TS, Giri PK, de Vera IM, Marciano DP, Kuruvilla DS, Shin Y, Blayo AL, Kamenecka TM, Burris TP, Griffin PR, and Kojetin DJ. (2014) An alternate binding site for PPARγ ligands. Nat Commun 5, 3571

30.    Srinivasan S, Nwachukwu JC, Parent AA, Cavett V, Nowak J, Hughes TS, Kojetin DJ, Katzenellenbogen JA, and Nettles KW. (2013) Ligand-binding dynamics rewire cellular signaling via estrogen receptor-alpha. Nat Chem Biol 9, 326-332

29.    Burris TP, Solt LA, Wang Y, Crumbley C, Banerjee S, Griffett K, Lundasen T, Hughes T, and Kojetin DJ. (2013) Nuclear receptors and their selective pharmacologic modulators. Pharmacol Rev 65, 710-778

28.    Kojetin DJ, and Burris TP. (2013) Small Molecule Modulation of Nuclear Receptor Conformational Dynamics: Implications for Function and Drug Discovery. Mol Pharmacol 83, 1-8

27.    Wang Y, Solt LA, Kojetin DJ, and Burris TP. (2012) Regulation of p53 stability and apoptosis by a ROR agonist. PloS one 7, e34921

26.    Solt LA, Wang Y, Banerjee S, Hughes TS, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R, You S-H, Takahashi JS, Butler A, Kamenecka TM, and Burris TP. (2012) Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists. Nature 485, 62-68

25.    Shin Y, Noel R, Banerjee S, Kojetin D, Song X, He Y, Lin L, Cameron MD, Burris TP, and Kamenecka TM. (2012) Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbalpha. Bioorg Med Chem Lett 22, 4413-4417

24.    Noel R, Song X, Shin Y, Banerjee S, Kojetin D, Lin L, Ruiz CH, Cameron MD, Burris TP, and Kamenecka TM. (2012) Synthesis and SAR of tetrahydroisoquinolines as Rev-erbalpha agonists. Bioorg Med Chem Lett 22, 3739-3742

23.    Hughes TS, Chalmers MJ, Novick S, Kuruvilla DS, Chang MR, Kamenecka TM, Rance M, Johnson BA, Burris TP, Griffin PR, and Kojetin DJ. (2012) Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism. Structure 20, 139-150

22.    Doerdelmann T, Kojetin DJ, Baird-Titus JM, Solt LA, Burris TP, and Rance M. (2012) Structural and biophysical insights into the ligand-free Pitx2 homeodomain and a ring dermoid of the cornea inducing homeodomain mutant. Biochemistry 51, 665-676

21.    Doerdelmann T, Kojetin DJ, Baird-Titus JM, and Rance M. (2012) (1)H, (1)(3)C and (1)(5)N chemical shift assignments for the human Pitx2 homeodomain in complex with a 22-base hairpin DNA. Biomol NMR Assign 6, 79-81

20.    Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Wang Y, Busby SA, Pascal BD, Garcia-Ordonez RD, Bruning JB, Istrate MA, Kojetin DJ, Dodge JA, Burris TP, and Griffin PR. (2011) DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex. Nat Struct Mol Biol 18, 556-563

19.    Solt LA, Kojetin DJ, and Burris TP. (2011) The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis. Future Med Chem 3, 623-638

18.    Refaei MA, Combs A, Kojetin DJ, Cavanagh J, Caperelli C, Rance M, Sapitro J, and Tsang P. (2011) Observing selected domains in multi-domain proteins via sortase-mediated ligation and NMR spectroscopy. J Biomol NMR 49, 3-7

17.    Doerdelmann T, Kojetin DJ, Baird-Titus JM, and Rance M. (2011) 1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain and a R24H homeodomain mutant. Biomol NMR Assign 5, 105-107

16.    Kumar N, Kojetin DJ, Solt LA, Kumar KG, Nuhant P, Duckett DR, Cameron MD, Butler AA, Roush WR, Griffin PR, and Burris TP. (2011) Identification of SR3335 (ML-176): A Synthetic RORalpha Selective Inverse Agonist. ACS Chem Biol 6, 218-22

15.    Kojetin D, Wang Y, Kamenecka TM, and Burris TP. (2011) Identification of SR8278, a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB. ACS Chem Biol 6, 131-4

14.    Crumbley C, Wang Y, Kojetin DJ, and Burris TP. (2010) Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene. J Biol Chem 285, 35386-35392

13.    Kojetin DJ, McLaughlin PD, Thompson RJ, Dubnau D, Prepiak P, Rance M, and Cavanagh J. (2009) Structural and motional contributions of the Bacillus subtilis ClpC N-domain to adaptor protein interactions. J Mol Biol 387, 639-652

12.    Sullivan DM, Bobay BG, Kojetin DJ, Thompson RJ, Rance M, Strauch MA, and Cavanagh J. (2008) Insights into the nature of DNA binding of AbrB-like transcription factors. Structure 16, 1702-1713

11.    Kojetin DJ, Burris TP, Jensen EV, and Khan SA. (2008) Implications of the binding of tamoxifen to the coactivator recognition site of the estrogen receptor. Endocr Relat Cancer 15, 851-870

10.    Kojetin DJ, Sullivan DM, Thompson RJ, and Cavanagh J. (2007) Classification of response regulators based on their surface properties. Methods Enzymol 422, 141-169

9.    Kojetin DJ, McLaughlin PM, Venters RA, Thompson RJ, Rance M, and Cavanagh J. (2007) NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC. Biomol NMR Assign 1, 163-5

8.    Kojetin DJ, Venters RA, Kordys DR, Thompson RJ, Kumar R, and Cavanagh J. (2006) Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K). Nat Struct Mol Biol 13, 641-647

7.    Venters RA, Coggins BE, Kojetin D, Cavanagh J, and Zhou P. (2005) (4,2)D Projection--reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K). J Am Chem Soc 127, 8785-8795

6.    Ulrich DL, Kojetin D, Bassler BL, Cavanagh J, and Loria JP. (2005) Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing. J Mol Biol 347, 297-307

5.    Kojetin DJ, Thompson RJ, Benson LM, Naylor S, Waterman J, Davies KG, Opperman CH, Stephenson K, Hoch JA, and Cavanagh J. (2005) Structural analysis of divalent metals binding to the Bacillus subtilis response regulator Spo0F: the possibility for in vitro metalloregulation in the initiation of sporulation. Biometals 18, 449-466

4.    Lutz W, Frank EM, Craig TA, Thompson R, Venters RA, Kojetin D, Cavanagh J, and Kumar R. (2003) Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy. Biochem Biophys Res Commun 303, 1186-1192

3.    Kojetin DJ, Thompson RJ, and Cavanagh J. (2003) Sub-classification of response regulators using the surface characteristics of their receiver domains. FEBS Lett 554, 231-236

2.    Helton TD, Kojetin DJ, Cavanagh J, and Horne WA. (2002) Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Cav2.1 Ca2+ channels. J Neurosci 22, 9331-9339

1.    Phillips CL, Arend LJ, Filson AJ, Kojetin DJ, Clendenon JL, Fang S, and Dunn KW. (2001) Three-dimensional imaging of embryonic mouse kidney by two-photon microscopy. Am J Pathol 158, 49-55